Single-molecule direct RNA sequencing without cDNA synthesis
نویسندگان
چکیده
منابع مشابه
Single molecule sequencing of the M13 virus genome without amplification
Next generation sequencing (NGS) has revolutionized life sciences research. However, GC bias and costly, time-intensive library preparation make NGS an ill fit for increasing sequencing demands in the clinic. A new class of third-generation sequencing platforms has arrived to meet this need, capable of directly measuring DNA and RNA sequences at the single-molecule level without amplification. ...
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ژورنال
عنوان ژورنال: Wiley Interdisciplinary Reviews: RNA
سال: 2011
ISSN: 1757-7004
DOI: 10.1002/wrna.84